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⚠️ NOT FOR HUMAN CONSUMPTION – FOR RESEARCH PURPOSES ONLY ⚠️ LL‑37A synthetic and human-derived antimicrobial peptide (37 amino acids) of the cathelicidin family, active in innate immunity and investigated across multiple research domains including infection, immunomodulation, and tissue repair. Form: Lyophilized powder Purity: >98% (HPLC) Storage: Store desiccated in a cool, dark place—long-term at −20 °C. After reconstitution, keep at 2–8 °C for short-term use; aliquot to avoid freeze-thaw cycles.(Sources: ProSpecBio storage & purity, Polaris Peptides high-quality listing) Research Highlights Broad-spectrum antimicrobial activity: Directly kills bacteria, viruses, and fungi through pore formation and membrane disruption, including multi‑drug resistant strains.(Sources: Ridyard – antimicrobial mechanism, Keshri 2025 – broad microbicidal activity) Immunomodulatory functions: Acts as a chemokine, promoting immune cell recruitment, modulates inflammation via LPS/LTA neutralization, and supports wound healing by stimulating keratinocyte migration and epidermal growth factor receptor activation.(Sources: Moreno‑Angarita – pore formation & immune roles, Wikipedia – immunomodulation & angiogenesis) Structural mechanism: Forms oligomeric and pore-like structures in membranes, including tetramers that disrupt lipid bilayers; the core region (residues 17–29) can self-assemble into fibrils with antimicrobial functionality.(Sources: Sancho‑Vaello – structural pore formation, Engelberg – fibril assembly of active core) Cancer and viral interactions: Under investigation for anticancer effects (eg, apoptosis induction) and for reducing viral infections—such as inhibiting SARS-CoV-2 via binding to ACE2 or blocking viral receptor interaction.(Sources: Lu 2022 - anticancer roles, Tocris data - viral entry inhibition) This compound is strictly intended for laboratory research use only.It is not approved for human or veterinary use, not a dietary supplement, and must not be used to diagnose, treat, cure, or prevent any disease or condition. FOR LABORATORY USE ONLY. NOT FOR HUMAN CONSUMPTION.

LL-37 (5mg)

€40.00Price
Quantity
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